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化驗
97%
光學活性
[α]20/D +31°, c = 1 in toluene
折射率
n20/D 1.4853 (lit.)
bp
74-76 °C/2 mmHg (lit.)
密度
1.025 g/mL at 25 °C (lit.)
SMILES 字串
OC[C@@H]1CCCN1
InChI
1S/C5H11NO/c7-4-5-2-1-3-6-5/h5-7H,1-4H2/t5-/m0/s1
InChI 密鑰
HVVNJUAVDAZWCB-YFKPBYRVSA-N
一般說明
(S)-(+)-2-吡咯烷基甲醇又称为(S)-(+)-脯氨醇,在手性有机物合成中用作手性合成砌块。还可用作不对称合成的手性助剂和不对称催化的手性配体。
應用
(S)-(+)-2-吡咯烷基甲醇可作为起始原料合成(S)-α,α-二芳基-2-吡咯烷基甲醇。在合成中起着赋予终产物手性的重要作用。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
186.8 °F - closed cup
閃點(°C)
86 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
Chemical record (New York, N.Y.), 5(2), 70-80 (2005-04-13)
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A highly efficient route for the synthesis of valuable 3,4-substituted chromenone derivatives by the reaction of 1,3-diketones with aldehydes in the presence of l-proline was developed. The reactions take advantage of readily available starting materials and follow a Knoevenagel condensation/Michael
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The photochirogenesis of 2-anthracenecarboxylic acid (AC) complexed to a hydrogen-bonding template (TKS159) was investigated to obtain mechanistic information on how chirogenesis is achieved for the dimerization of AC. Complexation of AC to TKS159 leads to the shielding of one of
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The Journal of organic chemistry, 77(21), 9846-9851 (2012-10-12)
The intramolecular aminohydroxylation of N-alkenylsulfonamides proceeded under heavy metal-free conditions to give substituted prolinol derivatives in high yields. Oxone activated by catalytic Brønsted acid worked well as an electrophilic oxidant for this reaction.
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