G7403

Glycin

≥99% (titration), suitable for electron microscopy, BioXtra

• Synonym(e): Aminoessigsäure, Aminoethansäure, Glycokoll
• Lineare Formel: NH₂CH₂COOH
• CAS-Nummer: 56-40-6
• Molekulargewicht: 75.07
• Beilstein: 635782
• EG-Nummer: 200-272-2
• MDL-Nummer: MFCD00008131
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 24895306
• NACRES: NA.26

Eigenschaften

• product name: Glycin, BioXtra, ≥99% (titration)
• Produktlinie: BioXtra
• Qualitätsniveau: 200
• Assay: ≥99% (titration)
• Form: powder
• Methode(n): electron microscopy: suitable
• Verunreinigungen: Insoluble matter, passes filter test
• Glührückstand: ≤0.05%
• Verlust: ≤0.05% loss on drying, HV, 20-26 °C
• Farbe: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp (Schmelzpunkt): 240 °C (dec.) (lit.)
• Löslichkeit: 1 M HCl: 1 M, clear, colorless
• Anionenspuren: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• Kationenspuren: Al: ≤0.0005%; As: ≤0.00001%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; NH₄⁺: ≤0.02%; Na: ≤0.02%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• Absorption: ≤0.04 at 260 in 1 M HCl at 1 M; ≤0.04 at 280 in 1 M HCl at 1 M
• SMILES String: NCC(O)=O
• UV-Absorption: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: 0.003; λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChIKey: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Grin2a(24409)

Beschreibung

Anwendung

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biochem./physiol. Wirkung

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Hemmender Neurotransmitter im Rückenmark; allosterischer Regulator von NMDA-Rezeptoren.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)