50046

Glycin

≥99.0% (NT), BioUltra

• Synonym(e): Aminoessigsäure, Aminoethansäure, Glycokoll
• Lineare Formel: NH₂CH₂COOH
• CAS-Nummer: 56-40-6
• Molekulargewicht: 75.07
• Beilstein: 635782
• EG-Nummer: 200-272-2
• MDL-Nummer: MFCD00008131
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 57651233
• NACRES: NA.26

Eigenschaften

• product name: Glycin, BioUltra, for molecular biology, ≥99.0% (NT)
• Qualität: for molecular biology
• Qualitätsniveau: 200
• Produktlinie: BioUltra
• Assay: ≥99.0% (NT)
• Form: crystalline
• Verunreinigungen: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• Glührückstand: ≤0.05% (as SO₄)
• Verlust: ≤0.05% loss on drying, HV, 20-26 °C
• Farbe: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp (Schmelzpunkt): 240 °C (dec.) (lit.)
• Löslichkeit: 1 M HCl: 1 M at 20 °C, clear, colorless
• Anionenspuren: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• Kationenspuren: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤200 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES String: NCC(O)=O
• λ: 1 M in 1 M HCl
• UV-Absorption: λ: 260 nm A_max: 0.05; λ: 280 nm A_max: 0.05
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChIKey: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Grin2a(24409)

Beschreibung

Anwendung

Glycine has been used as a component of the viral extraction mixture for adenovirus viral extraction.

Biochem./physiol. Wirkung

Glycine is a non-essential amino acid. It is involved in the synthesis of purines, serine and porphyrins. Glycine-gated channels mediate the influx of calcium through cell membranes. It also acts as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. In cancer cells, the synthesis of glycine might be increased due to increased demand for the amino acid.

Hemmender Neurotransmitter im Rückenmark; allosterischer Regulator von NMDA-Rezeptoren.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)