188204

p-Toluolsulfonylmethylisocyanid

98%

• Synonym(e): (p-Tolylsulfonyl)-Methylisocyanid, TosMIC, Tosylmethylisocyanid
• Lineare Formel: CH₃C₆H₄SO₂CH₂NC
• CAS-Nummer: 36635-61-7
• Molekulargewicht: 195.24
• Beilstein: 3592382
• EG-Nummer: 253-140-1
• MDL-Nummer: MFCD00000005
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24851306
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 109-113 °C (lit.)
• Löslichkeit: water: slightly soluble
• Funktionelle Gruppe: amine; isonitrile; sulfone
• Lagertemp.: 2-8°C
• SMILES String: Cc1ccc(cc1)S(=O)(=O)C[N+]#[C-]
• InChI: 1S/C9H9NO2S/c1-8-3-5-9(6-4-8)13(11,12)7-10-2/h3-6H,7H2,1H3
• InChIKey: CFOAUYCPAUGDFF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

p-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles. It is a versatile synthon in organic chemistry, extensively used for the synthesis of heterocyclic compounds.

Anwendung

Reagent for use in the preparation of biologically active pyrroles and imidazoles.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330
• P-Sätze: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Zusätzliche Gefahrenhinweise: EUH032
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges