143502

Trimethylessigsäureanhydrid

99%

• Synonym(e): Pivalinsäureanhydrid, 2,2-Dimethyl-propionsäure-anhydrid
• Lineare Formel: [(CH₃)₃CCO]₂O
• CAS-Nummer: 1538-75-6
• Molekulargewicht: 186.25
• Beilstein: 386552
• EG-Nummer: 216-263-1
• MDL-Nummer: MFCD00008842
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848589
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 99%
• Form: liquid
• Brechungsindex: n20/D 1.409 (lit.)
• bp: 193 °C (lit.)
• Dichte: 0.918 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: anhydride; ester
• SMILES String: CC(C)(C)C(=O)OC(=O)C(C)(C)C
• InChI: 1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3
• InChIKey: PGZVFRAEAAXREB-UHFFFAOYSA-N

Beschreibung

Anwendung

Acylation and esterification reagent for anilines and phenols, respectively.

Trimethylacetic anhydride was used:

• in solid-phase oligonucleotide synthesis
• in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
• as acylation and esterification reagent for anilines
• as acylation and esterification reagent for phenols

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H317,H319,H335
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 162.5 °F - closed cup
• Flammpunkt (°C): 72.5 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter