D7910
3,4-Dichloroisocoumarin
serine protease inhibitor
동의어(들):
3,4-DCI, 3,4-Dichloro-2-benzopyran-1-one
로그인조직 및 계약 가격 보기
크기 선택
5 MG
₩459,694
10 MG
₩806,215
25 MG
₩1,568,886
₩459,694
구입 가능 여부는 고객센터에 문의하십시오.
모든 사진(3)
크기 선택
보기 변경
5 MG
₩459,694
10 MG
₩806,215
25 MG
₩1,568,886
About This Item
실험식(Hill 표기법):
C9H4Cl2O2
CAS Number:
Molecular Weight:
215.03
Beilstein:
6802625
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77
₩459,694
구입 가능 여부는 고객센터에 문의하십시오.
추천 제품
애플리케이션
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.[1]
기타 정보
Effective concentration 5-100 μM.
수량
Half-life = 20 min at pH 7.5.
기질
Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
A Weihofen et al.
The Journal of biological chemistry, 275(40), 30951-30956 (2000-08-02)
Signal peptides of secretory and membrane proteins are generated by proteolytic processing of precursor proteins after insertion into the endoplasmic reticulum membrane. Liberated signal peptides can be further processed, and the resulting N-terminal fragments are released toward the cytosol, where
V Conseil et al.
Antimicrobial agents and chemotherapy, 43(6), 1358-1361 (1999-05-29)
We investigated the effect of protease inhibitors on the asexual development of the protozoan parasite Toxoplasma gondii. Among the inhibitors tested only two irreversible serine protease inhibitors, 3,4-dichloroisocoumarin and 4-(2-aminoethyl)-benzenesulfonyl fluoride, clearly prevented invasion of the host cells by specifically
Diego López León et al.
iScience, 23(3), 100932-100932 (2020-03-11)
Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show
Premkumari Kumarathasan et al.
Particle and fibre toxicology, 15(1), 34-34 (2018-08-12)
There is a paucity of mechanistic information that is central to the understanding of the adverse health effects of source emission exposures. To identify source emission-related effects, blood and saliva samples from healthy volunteers who spent five days near a
K S Lang et al.
Cell death and differentiation, 11(2), 231-243 (2003-11-15)
Erythrocytes lack nuclei and mitochondria, the organelles important for apoptosis of nucleated cells. However, following increase of cytosolic Ca(2+) activity, erythrocytes undergo cell shrinkage, cell membrane blebbing and breakdown of phosphatidylserine asymmetry, all features typical for apoptosis in nucleated cells.
문서
Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.
Uncover properties and applications of the cysteine protease papain and find inhibitors, substrates, and other papain products.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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