L6026

Sodium dodecyl sulfate

BioXtra, ≥99.0% (GC)

• 동의어(들): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• UNSPSC 코드: 12161900
• eCl@ss: 39093306
• PubChem Substance ID: 24896426
• NACRES: NA.21

속성

• 생물학적 소스: synthetic (oragnic)
• Quality Level: 200
• 설명: anionic
• 제품 라인: BioXtra
• 분석: ≥99.0% (GC)
• 양식: powder
• 분자량: micellar avg mol wt 18,000
• 응집 번호: 62
• 불순물: Insoluble matter, passes filter test
• 손실: ≤0.5% loss on drying, HV, 20-25 °C
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• 전이 온도: cloud point >100 °C
• solubility: H₂O: 0.1 M, clear, colorless
• density: 0.496 g/cm³
• 음이온 미량물: chloride (Cl^-): ≤0.05%; phosphate (PO₄^3-): ≤0.0001%
• 양이온 미량물: Al: ≤0.0005%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.02%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• 흡수: ≤0.05 at 280 in H₂O at 0.1 M; ≤0.08 at 260 in H₂O at 0.1 M
• HLB: 40
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

설명

일반 설명

Sodium dodecyl sulfate (SDS) is a well-known anionic detergent widely used in scientific research to denature proteins′ secondary and tertiary structures. It consists of a 12-carbon non-polar chain with a negatively charged sulfate group at the end. SDS is instrumental in denaturing and solubilizing proteins, making it a fundamental component of procedures like polyacrylamide gel electrophoresis, where it helps determine protein molecular weights.Moreover, SDS acts as an organic sodium salt and serves dual roles as a detergent and a protein denaturant. Its distinctive feature is its anionic surfactant nature, characterized by a negative charge. This charge fosters interactions with proteins and lipids, leading to the creation of micellar structures. These micelles are essential for SDS′s capacity to effectively solubilize and stabilize proteins and lipids, enabling their detailed study and manipulation in scientific research. SDS′s amphipathic properties, stemming from a long-chain aliphatic group with an attached negatively charged sulfate, make it a valuable detergent for various biomolecular experiments and studies.

애플리케이션

Anionic detergent

Sodium dodecyl sulfate has been used as a:

• surfactant to evaluate cytochrome c affinity by using surface plasmon resonance[1]
• surfactant in particle enhanced immunoassays to inhibit aggregation of particles and to enhance single microsphere coupling[2]
• biofilm-disrupting agent[3]

특징 및 장점

• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
• Tested for trace levels of Anions and Cations
• High-purity product ideal for biochemical research purposes

기타 정보

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안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H318,H412
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): 338.0 °F
• Flash Point (°C): 170 °C
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges