L4509

Sodium dodecyl sulfate

ReagentPlus^®, ≥98.5% (GC)

• 동의어(들): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• UNSPSC 코드: 12161900
• eCl@ss: 39093306
• PubChem Substance ID: 24896370
• NACRES: NA.21

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 설명: anionic
• 제품 라인: ReagentPlus^®
• 분석: ≥98.5% (GC)
• 형태: powder
• 분자량: micellar avg mol wt 18,000
• 응집 번호: 62
• 불순물: <2.0% water (Karl Fischer)
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• 전이 온도: cloud point >100 °C
• solubility: water: soluble
• density: 0.425 g/cm³
• 양이온 미량물: Na: 7.0-9.0%
• HLB: 40
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

설명

일반 설명

Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is widely recognized as an anionic surfactant within the organosulfate class of organic compounds. Its effectiveness as a detergent spans both ionic and anionic conditions. SDS plays a critical role as a protein denaturant, facilitating the solubilization and denaturation of proteins in procedures like protein extraction and SDS-PAGE. Its significance in the electrophoretic separation of proteins and lipids establishes its indispensability for the examination of these molecules in diverse biological experiments. In conclusion, Sodium dodecyl sulfate proves to be an indispensable element in the exploration of biological molecules within the realms of biochemical and cell biology research.

애플리케이션

Sodium dodecyl sulphate (SDS) has been used:

• in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds
• to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation
• in the decellularization of porcine heart valve tissue
• to treat sperm for in vitro induction of sperm decondensation

Anionic detergent

생화학적/생리학적 작용

Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase).

특징 및 장점

• Suitable for Cell Biology and Biochemical Research
• High purity chemical suitable for multiple research applications

기타 정보

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법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H228,H302 + H332,H315,H318,H335,H412
• 예방조치 성명서: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 4.1B - Flammable solid hazardous materials
• WGK: WGK 2
• Flash Point (°F): 338.0 °F
• Flash Point (°C): 170 °C
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges