75746

Sodium dodecyl sulfate

≥99.0% (GC), dust-free pellets

• 동의어(들): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• UNSPSC 코드: 12161900
• eCl@ss: 39093306
• PubChem Substance ID: 329766677
• NACRES: NA.25

속성

• 설명: anionic
• 분석: ≥99.0% (GC)
• 형태: rod
• 분자량: average mol wt 18,000
• 응집 번호: 62
• 손실: ≤5% loss on drying
• CMC: 7-10 (lit.)
• mp: 204 - 207 °C (399 - 405 °F); 204-207 °C (lit.)
• 전이 온도: cloud point >100 °C(lit.)
• solubility: H₂O: soluble 0.29 gm in 10ml, clear, colorless; H₂O: 0.1 M at 20 °C, clear, colorless; 130 g/L at 20 °C (68 °F)
• density: 1 g/cm³
• 음이온 미량물: chloride (Cl^-): ≤200 mg/kg
• 양이온 미량물: Ca: ≤25 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤200 mg/kg; Mg: ≤20 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• HLB: 40(lit.)
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

설명

일반 설명

Sodium dodecyl sulfate (SDS) is an organic sodium salt used as both a detergent and a protein denaturant in biochemical research. Its unique structure includes a long-chain aliphatic group with a negatively charged sulfate, making it an effective agent for denaturing proteins. This property is especially valuable in electrophoresis, a technique used to separate and analyze macromolecules like proteins. SDS, with its negative charge, interacts with proteins and lipids to create micellar structures, aiding in solubilizing and stabilizing these biomolecules.

애플리케이션

Sodium dodecyl sulfate (SDS) has been used:

• as a negatively charged surfactant to study its effects on filtration flux and membrane fouling during the microfiltration of the surfactant-stabilized oil emulsion
• as a component of plant extraction buffer, and transferring buffer for western blot
• as a component of 5× Laemmli sample buffer (5× LB) and 10× SDS running buffer for sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblot

Anionic detergent

생화학적/생리학적 작용

Sodium dodecyl sulfate (SDS) effectively binds to the positively charged and the hydrophobic residues of proteins via sulfate groups and alkyl chains. It functions as a vital detergent in the domain of structural biology and protein folding/unfolding studies. SDS can stimulate the creation of α-helices in a protein structure. It has the ability to promote cooperative unfolding in several proteins including bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations. 

특징 및 장점

• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
• Tested for trace levels of Anions and Cations
• High-purity product ideal for biochemical research purposes

기타 정보

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안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H318,H412
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): 338.0 °F
• Flash Point (°C): 170 °C
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges