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Merck
모든 사진(1)

주요 문서

56197

Supelco

3-Hydroxypicolinic acid

matrix substance for MALDI-MS, ≥99.0% (HPLC)

동의어(들):

3-HPA, 3-Hydroxypyridine-2-carboxylic acid

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About This Item

실험식(Hill 표기법):
C6H5NO3
CAS Number:
Molecular Weight:
139.11
Beilstein:
118954
EC Number:
MDL number:
UNSPSC 코드:
12000000
PubChem Substance ID:
NACRES:
NA.21
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Grade

matrix substance for MALDI-MS

Quality Level

분석

≥99.0% (HPLC)

양식

powder or crystals

분석물 화학적 분류

oligonucleotides, oligosaccharides

기술

MALDI-MS: suitable

mp

213-218 °C (lit.)

양이온 미량물

Ba: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤20 mg/kg
K: ≤20 mg/kg
Mg: ≤50 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

적합성

suitable for matrix substance for MALDI-MS

SMILES string

OC(=O)c1ncccc1O

InChI

1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)

InChI key

BRARRAHGNDUELT-UHFFFAOYSA-N

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애플리케이션

3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.[1][2]

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

3-Hydroxypicolinic acid has been used in the study conducted to isolate and characterize bacteria degrading-quinoline in subsurface sediments.[3]

관련 제품

제품 번호
설명
가격

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

P Juhasz et al.
Carbohydrate research, 270(2), 131-147 (1995-04-30)
Molecular weights of heparin-derived oligosaccharides ranging from disaccharides to hexadecasaccharides have been determined by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. While these compounds ionize poorly or not at all when used as such, a strong signal can be obtained
K Tang et al.
Nucleic acids research, 23(16), 3126-3131 (1995-08-25)
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry was used to analyze short DNA duplex probes with one strand immobilized on solid supports (straptavidin-coated magnetic beads or controlled pore glass beads). Only the non-immobilized strand could be detected. Partial denaturation
Gas-phase diagnostics and LIF-imaging of 3-hydroxypicolinic acid MALDI-matrix plumes
Puretzky AA and Geohegan DB
Chemical Physics Letters, 286(5-6), 425-432 (1998)
H Suzuki et al.
Analytical chemistry, 69(22), 4554-4559 (1998-01-07)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), has been used for structure characterization of 1-aminopyrene-3,6,8-trisulfonate (APTS)-derivatized oligosaccharides previously separated by capillary electrophoresis (CE). The resolved components were first isolated by employing an automated high-resolution fraction collector. Using on-probe sample
Isolation and characterization of quinoline-degrading bacteria from subsurface sediments.
Applied and Environmental Microbiology, 55 (4), 1029-1032 (1989)

관련 콘텐츠

ZipTip® micro-SPE pipette tips are used as a single-step desalting, concentration, and purification tool for complex samples before mass spec analyses.

질문

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 답변
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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