42597
3′-Deoxythymidine 5′-triphosphate sodium salt solution
BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)
동의어(들):
2′,3′-Dideoxythymidine 5′-triphosphate, ddTTP
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C10H16N2NaO13P3
CAS Number:
Molecular Weight:
488.15
MDL number:
UNSPSC 코드:
41116105
PubChem Substance ID:
추천 제품
제품 라인
BioChemika
grade
puriss. p.a.
분석
≥98.0% (HPLC)
농도
10.0-11.0 mmol/L (UV)
기술
MALDI-MS: suitable
불순물
≤1.5% ddNDP (HPLC)
적합성
corresponds for UV test
저장 온도
−20°C
SMILES string
[Na+].CC1=CN([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
InChI
1S/C10H17N2O13P3.Na/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17;/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17);/q;+1/p-1/t7-,8+;/m0./s1
InChI key
QJSZKDPCBDXBCK-KZYPOYLOSA-M
일반 설명
3′-Deoxythymidine 5′-triphosphate sodium (ddTTP) is a sugar-modified dTTP analogue which is selective inhibitor of HIV-associated reverse transcriptase (HIV-RT). It is also seen to inhibit the activity of DNA polymerase α.
포장
packaging : 1 μmol (approx. 91-100 μL)
관련 제품
제품 번호
설명
가격
교체됨
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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Nucleic acids research, 42(5), 3125-3137 (2013-12-29)
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E Matthes et al.
Biochemical and biophysical research communications, 148(1), 78-85 (1987-10-14)
The sugar-modified dTTP analogues 2',3'-didehydro-2',3'-dideoxy-thymidine 5'-triphosphate (ddeTTP), 2',3'-dideoxythymidine 5'-triphosphate (ddTTP), 3'-fluorothymidine 5'-triphosphate (FdTTP), and 3'-azidothymidine 5'-triphosphate (N3dTTP) are demonstrated to be very effective and selective inhibitors of the HIV-associated reverse transcriptase (HIV-RT). This conclusion is based on a comparison of
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