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Merck
모든 사진(1)

문서

C-117

Supelco

Corticosterone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

실험식(Hill 표기법):
C21H30O4
CAS Number:
Molecular Weight:
346.46
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

clinical testing
clinical testing

형식

single component solution

저장 온도

−20°C

SMILES string

CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO

InChI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

InChI key

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

일반 설명

Corticosterone is a corticosteroid and aldosterone precursor produced in the adrenal glands. Serum corticosterone levels are measured by LC-MS/MS for newborn screening and diagnosis of 11-hydroxylase deficiency.

애플리케이션


  • Corticosterone ELISA kit for stress hormone research: Research has demonstrated the efficacy of corticosterone ELISA kits in measuring stress hormone levels, contributing significantly to studies on adrenal gland function and stress-related disorders. This application is vital for in vivo corticosterone analysis, allowing detailed monitoring of hormone fluctuations in response to various stressors (Ornelas et al., 2024).

  • High-purity corticosterone for receptor binding assays: Corticosterone solutions are extensively used in receptor binding assays to understand corticosteroid receptor interactions. These studies are crucial for advancing knowledge in endocrinology biochemical studies, particularly in mapping corticosteroid pathways and their effects within the body (Xie et al., 2024).

  • Synthetic corticosterone solution for endocrine studies: Synthetic corticosterone is employed in clinical experimental setups to examine the endocrine system′s response under controlled conditions. This usage is particularly evident in studies focusing on the adaptation of the endocrine system to external stress factors and its impact on overall physiological health (Costa et al., 2024).

  • Liquid corticosterone for stress response research: Liquid formulations of corticosterone are pivotal in conducting stress response research, providing a consistent and measurable means of administering this hormone to study its acute and chronic effects on animal behavior and physiological responses (Ornelas et al., 2023).

  • Corticosterone reagent for glucocorticoid receptor experiments: As a reagent, corticosterone is integral to glucocorticoid receptor experiments, which are essential for understanding glucocorticoid receptor dynamics and their implications in various physiological processes, including immune response and metabolic regulation (Heraudeau et al., 2023).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup


시험 성적서(COA)

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T V Shemenkova et al.
Bulletin of experimental biology and medicine, 154(4), 464-466 (2013-03-15)
ACTH1-24(1 mg/kg) administered to 5-7-day-old rats reduced their locomotor activity and did not alter blood levels of corticosterone. ACTH administration on postnatal days 12-14 increased corticosterone levels, but had no effect on locomotor activity. Thus, the behavioral effect of ACTH
Kathan Chintamaneni et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 304(9), R782-R789 (2013-03-15)
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프로토콜

The conversion of clinical methods to LC/MS/MS offers advantages; however, is accompanied by a few limitations, notably interference effects from the endogenous sample matrix.

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