857127P
Avanti
17:0 Lyso PA
1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder
동의어(들):
heptadecanoyl lysophosphatidic acid; 1-heptadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(17:0/0:0); 17:0 LPA; 110679
로그인조직 및 계약 가격 보기
모든 사진(2)
크기 선택
보기 변경
25 MG
₩616,816
About This Item
실험식(Hill 표기법):
C20H40O7PNa
CAS Number:
Molecular Weight:
446.49
MDL number:
UNSPSC 코드:
51191904
NACRES:
NA.25
추천 제품
분석
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
양식
powder
포장
pkg of 1 × 25 mg (857127P-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand 857127P
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100 nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.[1]
애플리케이션
17:0 Lyso PA is suitable to use as an internal standard:
- for mass spectrometric determination of lysophosphatidic acid molecular species in mouse peritoneal macrophages[2]
- in the quantification of the lipid species released from extended synaptotagmin 2 (E-SYT2) expressed in mammalian cells by liquid chromatography with tandem mass spectrometry (LC-MS/MS)[3]
- for the extraction of lipids from brain homogenate[4]
- to extract lipids from the stomach washing solution for the determination of lysophosphatidic acid in a mouse stomach fluid[5]
생화학적/생리학적 작용
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).[1]
포장
5 mL Amber Glass Screw Cap Vial (857127P-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
No data available
Flash Point (°C)
No data available
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2\beta (group VIA phospholipase A2)
Ashley JW, et al.
The Journal of Biological Chemistry, 291(44), 23268- 23281 (2016)
Comprehensive phospholipid and sphingomyelin profiling of different brain regions in mouse model of anxiety disorder using online two-dimensional (HILIC/RP)-LC/MS method
Berkecz R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 149, 308- 317 (2018)
Lysophosphatidic acid in medicinal herbs enhances prostaglandin E2 and protects against indomethacin-induced gastric cell damage in vivo and in vitro
Afroz S, et al.
Prostaglandins & other lipid mediators, 135, 36- 44 (2018)
Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
Dong Y, et al.
Mediators of Inflammation, 2017 (2017)
Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer
Schauder CM, et al.
Nature, 510(7506), 552-552 (2014)
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