850186P
Avanti
08:0 PI(3,4,5)P3
1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder
동의어(들):
PIP3[3′,4′,5′](8:0/8:0); 110667
로그인조직 및 계약 가격 보기
모든 사진(2)
크기 선택
보기 변경
100 μG
₩155,397
500 μG
₩619,353
About This Item
실험식(Hill 표기법):
C25H62N4O22P4
CAS Number:
Molecular Weight:
894.67
MDL number:
UNSPSC 코드:
51191904
NACRES:
NA.25
추천 제품
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 100 μg (with stopper and crimp cap (850186P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850186P-500ug))
제조업체/상표
Avanti Research™ - A Croda Brand 850186P
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
일반 설명
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) is a less abundant lipid.[1]
애플리케이션
08:0 PI(3,4,5)P3 may be used as a control compound for assessing phosphoinositide 3-kinase activity.[2]
생화학적/생리학적 작용
포장
2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-500ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Baculovirus production of fully-active phosphoinositide 3-kinase alpha as a p85 alpha-p110 alpha fusion for X-ray crystallographic analysis with ATP competitive enzyme inhibitors
Sinnamon RH, et al.
Protein Expression and Purification, 73(2), 167-176 (2010)
Rays H Y Jiang et al.
Cell host & microbe, 11(2), 99-100 (2012-02-22)
Survival of blood stage malaria parasites requires extensive host cell remodeling, which is facilitated by secretion of parasite proteins via a dedicated protein export pathway. In a recent Cell paper, Bhattacharjee et al., (2012) describe PI(3)P binding as one of the
Sulochanadevi Baskaran et al.
Molecular cell, 47(3), 339-348 (2012-06-19)
Macroautophagy is essential to cell survival during starvation and proceeds by the growth of a double-membraned phagophore, which engulfs cytosol and other substrates. The synthesis and recognition of the lipid phosphatidylinositol 3-phosphate, PI(3)P, is essential for autophagy. The key autophagic
Thang Manh Khuong et al.
Neuron, 77(6), 1097-1108 (2013-03-26)
PI(3,4,5)P3 is a low-abundance lipid thought to play a role in the regulation of synaptic activity; however, the mechanism remains obscure. We have constructed novel split Venus-based probes and used superresolution imaging to localize PI(3,4,5)P3 at Drosophila larval neuromuscular synapses. We find
Kewei Ma et al.
Cellular signalling, 20(4), 684-694 (2008-02-06)
The PI3K-PKB pathway is an important and widely studied pathway in cell signaling. The enzyme activity of PI3K produces D-3 phosphoinositides, including the lipid second messengers PI(3,4,5)P3 and PI(3,4)P2. PI(3,4,5)P3 has been deemed to be the most important second messenger
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