SML2751

UCSF7447

≥98% (HPLC)

• 別名: 2-Bromo-4-chloro-N-[3-(1H-1,2,4-triazol-5-yl)phenyl]-benzenemethanamine, ZINC555417447
• 実験式（ヒル表記法）: C₁₅H₁₂BrClN₄
• CAS番号: 2305480-97-9
• 分子量: 363.64
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: Brc1c(ccc(c1)Cl)CNc2cc(ccc2)c3[nH]ncn3
• InChI: 1S/C15H12BrClN4/c16-14-7-12(17)5-4-11(14)8-18-13-3-1-2-10(6-13)15-19-9-20-21-15/h1-7,9,18H,8H2,(H,19,20,21)
• InChI Key: QPTCYEYTAWEZNT-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447 advances the phase of the mouse circadian clock when administer at dusk.

brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable