The details of the manufacturing processing cannot be shared, for proprietary reasons, but the product is not sterile filtered. It is is packaged under aseptic conditions.
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フォーム
liquid
品質水準
比活性
(Antibacterial)
濃度
100 mg/mL in water
抗生物質活性スペクトル
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
作用機序
protein synthesis | interferes
保管温度
−20°C
SMILES記法
[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H]([C@@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([
InChI
1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-
InChI Key
QTENRWWVYAAPBI-YZTFXSNBSA-N
詳細
Chemical structure: aminoglycoside
アプリケーション
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
生物化学的／生理学的作用
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
保管および安定性
- Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
- Streptomycin: sulfate salt ratio is 1:1.5.
- The product is packed under aseptic conditions.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Repr. 2
保管分類コード
10 - Combustible liquids
WGK
WGK 3
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SBR00068-10ML:
SBR00068-VAR:
SBR00068-BULK:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
Daniela Lobenwein et al.
Journal of the American Heart Association, 4(10), e002440-e002440 (2015-10-29)
Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular aortic repair. Shock wave treatment was shown to induce angiogenesis and regeneration in ischemic tissue by modulation of early inflammatory response via Toll-like receptor (TLR)
Rabia T Khan et al.
PloS one, 9(2), e88009-e88009 (2014-02-08)
Experimental animal models of Salmonella infections have been widely used to identify genes important in the host immune response to infection. Using an F2 cross between the classical inbred strain C57BL/6J and the wild derived strain MOLF/Ei, we have previously
Jiayun Zhu et al.
Cell cycle (Georgetown, Tex.), 14(12), 1809-1822 (2015-06-18)
Fanconi Anemia (FA) is a cancer predisposition syndrome and the factors defective in FA are involved in DNA replication, DNA damage repair and tumor suppression. Here, we show that FANCD2 is critical for genome stability maintenance in response to high-linear
Carlotta Alias et al.
Journal of cellular and molecular medicine, 19(9), 2098-2107 (2015-05-27)
Gynaecological leiomyosarcoma (gLMS) represent a heterogeneous group of soft tissue sarcoma, characterized by rare incidence, high aggressiveness and propensity to infiltrate secondary organs, poor prognosis and lethality, because of the lack of biological mechanisms that underlying their progression and effective
Marimuthu Subathra et al.
American journal of physiology. Renal physiology, 309(3), F204-F215 (2015-06-05)
Glycosphingolipids (GSLs) play a role in insulin resistance and diabetes, but their role in diabetic nephropathy (DN) has received limited attention. We used 9- and 17-wk-old nondiabetic db/m and diabetic db/db mice to examine the role of GSLs in DN.
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