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由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
BN-34, monoclonal
フォーム
buffered aqueous solution
交差性
canine, human, bovine, rat, mouse
濃度
~1 mg/mL
テクニック
ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: 0.15-0.3 μg/mL
western blot: suitable
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
詳細
Biotin is a bi-heterocyclic, essential water soluble vitamin and a cofactor synthesized in most of the plants and prokaryotes. Protein-bound biotin in usually found in dietary sources like meat, cereals, egg yolk, liver and some vegetables.
免疫原
biotinylated KLH
生物化学的／生理学的作用
Biotin functions as a coenzyme for acetyl CoA, pyruvate, propionyl-CoA and 3-methylcrotonyl-CoA carboxylases for the regulation of gluconeogenesis, lipid homeostasis, pleotropic gene expression and to replenish the intermediates of tricarboxylic cycle. Biotin bound to histones plays an important role in chromatin remodeling, DNA repair and repression of transposons to maintain genome stability. Inadequate biotin levels may lead to dermatitis, conjunctivitis, alopecia, and central nervous system abnormalities.
物理的形状
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SAB4200680-100UL:
SAB4200680-VAR:
SAB4200680-BULK:
IRO97633:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
この製品を見ている人はこちらもチェック
Yongzheng Xing et al.
Nature nanotechnology, 17(7), 708-713 (2022-04-29)
Membrane nanopores are key for molecular transport in biology, portable DNA sequencing1-4, label-free single-molecule analysis5-14 and nanomedicine5. Transport traditionally relies on barrel-like channels of a few nanometres width, but there is considerable scientific and technological interest for much wider structures
Molecular biology of biotin attachment to proteins
Chapman-Smith Anne and Cronan Jr JE
The Journal of Nutrition, 129(2), 477S-484S (1999)
Abigail M Wojtowicz et al.
Biomaterials, 31(9), 2574-2582 (2010-01-09)
Healing large bone defects and non-unions remains a significant clinical problem. Current treatments, consisting of auto and allografts, are limited by donor supply and morbidity, insufficient bioactivity and risk of infection. Biotherapeutics, including cells, genes and proteins, represent promising alternative
Hirotaka Takahashi et al.
PloS one, 11(6), e0156718-e0156718 (2016-06-02)
Ubiquitination is a key post-translational modification in the regulation of numerous biological processes in eukaryotes. The primary roles of ubiquitination are thought to be the triggering of protein degradation and the regulation of signal transduction. During protein ubiquitination, substrate specificity
Biotin: a timeless challenge for total synthesis
De Clercq PJ
Chemical Reviews, 97(6), 1755-1792 (1997)
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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