SAB2701209

Anti-ALDH1A2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: ALDH1A2, MGC26444, RALDH(II), RALDH2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: human, rat, mouse
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 500-10000
• NCBIアクセッション番号: AAH30589
• UniProtアクセッション番号: O94788
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ALDH1A2(8854)

詳細

免疫原

Recombinant fragment corresponding to a region within amino acids 278 and 518 of ALDH1A2 according to AAH30589

アプリケーション

Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的／生理学的作用

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

特徴および利点

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物理的形状

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317,H412
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 3 - Skin Sens. 1
• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable