SAB2500715

抗OGT抗体 ヤギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• 別名: 抗FLJ23071抗体, 抗HRNT1抗体, 抗MGC22921抗体, 抗O-GLCNAC抗体, 抗O-結合型N-アセチルグルコサミン(GlcNAc)トランスフェラーゼ(UDP-Nアセチルグルコサミン/ポリペプチドNアセチルグルコサミントランスフェラーゼ)抗体
• MDL番号: MFCD07370422
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: goat
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: rat, human
• テクニック: indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: O15294
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... OGT(8473)

詳細

詳細

O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) has 13.5 tetratricopeptide-repeats (TPR) and a globular catalytic domain. The gene encoding this protein is localized on human chromosome Xq13.1.

免疫原

NP_858058.1; NP_858059.1によるタンパク質配列の内部領域に由来するペプチド(C-YEHPKDLKLSDGR)。

生物化学的／生理学的作用

O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) has a role in the addition of O-linked N-acetylglucosamine (O-GlcNAc) to serine/threonine residues in the protein of interest. It is crucial for O-GlcNAcylation of RNA polymerase II. Absence of OGT has been shown to reduce transcription and pol II promoter occupancy. The gene is upregulated in breast cancer tissues, colon cancer, lung cancer and laryngeal cancer. This protein might be associated with tumorigenesis and metastasis.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

0.5 mg/mL Tris緩衝生理食塩水(0.5% BSA, 0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable