RAB0016

Human Angiopoietin-2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• 別名: Angiopoietin-2
• UNSPSCコード: 41116158
• NACRES: NA.32

特性

• 交差性: human
• 包装: kit of 96 wells (12 strips x 8 wells)
• テクニック: ELISA: suitable; capture ELISA: suitable
• 入力: sample type urine; sample type serum; sample type cell culture supernatant(s); sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 10 pg/mL; standard curve range: 4.12-3000 pg/mL
• 検出方法: colorimetric
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ANGPT2(285)

詳細

詳細

The Human Angiopoietin-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Angiopoietin-2 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human Angiopoietin-2

アプリケーション

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

生物化学的／生理学的作用

Angiopoietin-2 (ANGPT2) belongs to the family of angiogenic factors. ANGPT2 is a competitive antagonist of ANGPT1 and reduces vascular stabilization.[1] ANGPT2 is a potent marker for liver cancer.[1][2] ANGPT2 binds with tyrosine kinase with immunoglobulin-like and endothelial growth factor (EGF)-like domains 2 (Tie-2) and causes neoangiogenesis in liver cirrhosis.[2] Upregulation of ANGPT2 might have an adverse effect on kidney physiology and function. Overexpression of ANGPT2 leads to endothelial damage and dysfunction resulting in diabetic nephropathy in diabetic patients.[3] ANGPT2 is a potent marker for detecting lung cancer progression.[4] Upregulation of ANGPT2 promotes signal transduction for tumor progression in epithelial ovarian cancer.[5]

その他情報

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

キットの構成要素は別途購入可能です。

• RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Warning
• 危険有害性情報: H290
• 注意書き: P234 - P390
• 危険有害性の分類: Met. Corr. 1
• 保管分類コード: 8A - Combustible corrosive hazardous materials