M4199

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

lyophilized powder

• 別名: MOG (40-54)
• 実験式（ヒル表記法）: C₈₄H₁₂₇N₂₇O₂₁
• CAS番号: 507233-87-6
• 分子量: 1851.08
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: rat
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• 形状: lyophilized powder
• 色: white
• 溶解性: deionized water: soluble
• UniProtアクセッション番号: Q61885; Q63345
• 保管温度: −20°C
• 遺伝子情報: mouse ... Mog(17441) ; rat ... Mog(24558)

詳細

Amino Acid Sequence

Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly

生物化学的／生理学的作用

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

物理的形状

凍結乾燥品(0.1% TFA水溶液)。

その他情報

Lyophilized from 0.1% TFA in H2O

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable