This product has not been tested for platelet aggregation. The end user would have to determine suitability, although Collagen Type I has been sited in the literature in platelet aggregation studies. Collagen Type III and IV are more commonly cited, however. Please see the links below to review alternative Collagen products that have been successfully used by other researchers for platelet aggregation:
Human Collagen Type IV
https://www.sigmaaldrich.com/product/sigma/c7521
https://www.sigmaaldrich.com/US/en/product/sigma/h4417
Human Collagen Type III
https://www.sigmaaldrich.com/US/en/product/sigma/c4407
サイズを選択してください
| あなたへ/カタログ番号 | 在庫状況 | 単価 |
|---|---|---|
1 g | 出荷予測2026年6月01日from市川市大町368 | ¥12,400 |
5 g | 出荷予測2026年6月01日from市川市大町368 | ¥35,300 |
10 g | カートの在庫状況を確認する | ¥60,100 |
25 g | カートの在庫状況を確認する | ¥115,000 |
この商品について
General description
Application
ウシアキレス腱由来コラーゲンは、細長い原繊維の形で自然に生じるタンパク質です。ウシアキレス腱由来コラーゲンは、踵骨に入る前にコラーゲンがまず通過する必要がある線維軟骨領域の研究に使用できます。また、アキレス腱治癒におけるコラーゲン含量および架橋に対する増殖因子の作用に関する研究に使用できます。
Biochem/physiol Actions
Preparation Note
1 of 1
当該品目 | |||
|---|---|---|---|
| biological source bovine Achilles tendon | biological source bovine (calf) skin | biological source rat tail | biological source rat tail |
| technique(s) ELISA: suitable, activity assay: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| form powder | form solution (0.1% solution in 0.1 M acetic acid) | form powder | form liquid |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
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保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Is this collagen suitable as an agonist in platelet aggregation assays?
1 回答-
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Is this suitable for cell culture?
1 回答-
This product has not been tested for suitability in cell culture applications. Please see products C9791 and C8919 at the link below to review cell culture tested product options:
https://www.sigmaaldrich.com/substance/bovinecollagentypei123459007345役に立ちましたか?
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What is the most suitable solvent for this product?
1 回答-
As mentioned in the 'DESCRIPTION' section under 'Reconstitution'. This product is an insoluble collagen preparation. It is insoluble in water, aqueous buffers, dilute acid, and organic solvents. For use as a substrate in collagenase assays, this collagen can be prepared as a suspension in 50 mM TES buffer, pH 7.4 with 0.36 mM calcium chloride.
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Is it suitable to fabricate a 3D matrix with gelatin and water?
1 回答-
This collagen product is not tested for 3D gel formation. Residual acids from the extraction and purification process may impact the ability of the material to form a 3D matrix. However, there are several bovine collagen products that are recommended for this application. Please see the links below to review these product options:
Bovine Collagen Type I for 3D
https://www.sigmaaldrich.com/US/en/substance/bovinecollagentypei1234598765
Bovine Collagen Solutions for 3D
https://www.sigmaaldrich.com/US/en/substance/collagensolutionfrombovineskin1234598765役に立ちましたか?
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Do you have a nominal purity on this product?
1 回答-
The purity of this product is not tested. It is qualified for use as a substrate for collagenase.
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What application can Product No. C9879, Collagen from bovine, be used in?
1 回答-
This product is suitable for use as a substrate for collagenase. It is not suitable for use as an attachment factor in coating glassware.
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What is the molecular weight of product C9879, Collagen from bovine achilles tendon?
1 回答-
Since product C9879 is an insoluble collagen preparation, it is difficult to make any kind of molecular weight determination. However, based on the reported structure of this collagen, the expected molecular weight would be approximately 300 kDa.
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What is the structure of the Collagen from bovine - C9879?
1 回答-
The amino acid sequence of the primary structure is mainly a repeating motif with glycine in every third position, and a proline or 4-hydroxyproline frequently preceding the glycine residue.
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What is the Department of Transportation shipping information for this product?
1 回答-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How should Product No. C9879, Collagen from bovine, be reconstituted?
1 回答-
This product is an insoluble collagen preparation. It is insoluble in water, aqueous buffers, dilute acid, and organic solvents. A suspension can be prepared in 50 mM TES buffer, pH 7.4 with 0.36 mM calcium chloride, but not a clear solution.
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