M2518

メナジオン重亜硫酸ナトリウム

BioReagent, suitable for cell culture, ≥95% (TLC)

• 別名: 2-メチル-1,4-ナフトキノン重亜硫酸ナトリウム
• 実験式（ヒル表記法）: C₁₁H₉NaO₅S
• CAS番号: 130-37-0
• 分子量: 276.24
• EC Number: 204-987-0
• MDL番号: MFCD00051456
• UNSPSCコード: 12352205
• PubChem Substance ID: 24896741
• NACRES: NA.75

特性

• 由来生物: synthetic (organic)
• 製品種目: BioReagent
• アッセイ: ≥95% (TLC)
• 形状: powder
• 分子量: M_w 276.24 g/mol
• テクニック: cell culture | mammalian: suitable; cell culture | plant: suitable
• 色: white to off-white
• 溶解性: water: soluble 50 mg/mL, clear, colorless to light yellow
• 保管温度: −20°C
• SMILES記法: [Na+].CC1(CC(=O)c2ccccc2C1=O)S([O-])(=O)=O
• InChI: 1S/C11H10O5S.Na/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;/h2-5H,6H2,1H3,(H,14,15,16);/q;+1/p-1
• InChI Key: XDPFHGWVCTXHDX-UHFFFAOYSA-M

詳細

アプリケーション

Menadione sodium bisulfite has been used:

• as a free radical inducer to study its effects on oxidative stress in sunflower seedlings
• as a positive control to produce mitochondrial O₂ during the measurement of O₂ in human proximal tubular cell lines
• as a redox-cycling mitochondrial pro-oxidant to study its effects on protein kinase B (AKT) and mechanistic target of rapamycin (mTOR) signaling in cardiac cells

生物化学的／生理学的作用

Menadione sodium bisulfite (MSB) is a derivative of vitamin K3 and has been studied in the treatment of hemorrhagic diseases like hypoprothrombinemia and neonatal hemorrhage, caused due to vitamin K3 deficiency. It is also considered a nutritional supplement for animals. MSB shows anticancer effects. It also protects plants from biotic and abiotic stress.

その他情報

水溶性ビタミンK₃。

免責事項

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H410
• 注意書き: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• 危険有害性の分類: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves