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Merck

I9010

Sigma-Aldrich

抗ヒトIgG (Fab特異的) ヤギ宿主抗体

whole antiserum

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

goat

結合体

unconjugated

抗体製品の状態

whole antiserum

抗体製品タイプ

secondary antibodies

クローン

polyclonal

含みます

15 mM sodium azide

テクニック

indirect ELISA: 1:30,000
quantitative precipitin assay: 4.0 mg/mL

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

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詳細

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. Immunoglobulins have two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. About 70 percent of the total immunoglobulin consists of IgG.

特異性

Reactivity is observed versus purified human IgA, IgM, Bence Jones Kappa and Bence Jones Lambda myeloma proteins. No reactivity is observed versus Fc fragment of human IgG.

アプリケーション

Anti-Human IgG (Fab specific) antibody produced in goat has been used in immunological assays. It has also been used in cellulose substrates as immobilized anti-hIgG to detect human immunoglobulin G (hIgG) from fluid matrices.
Anti-Human IgG (Fab specific) antibody produced in goat was used in capture ELISA at a dilution of 1:10,000.

生物化学的/生理学的作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

物理的形状

Supplied as a liquid containing 15 mM sodium azide as a preservative.

調製ノート

delipidized

保管および安定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

I9010-BULK:
I9010-2ML:
I9010-VAR:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Hannes Orelma et al.
Biomacromolecules, 13(9), 2802-2810 (2012-07-27)
We investigated the adsorption and chemical conjugation of avidin and its deglycosylated form, neutravidin, on films of regenerated and nanofibrillar cellulose. The dynamics and extent of biomolecular attachment were monitored in situ by quartz crystal microbalance microgravimetry and ex situ
Label-free biodetection using capacitive micromachined ultrasonic transducers (CMUTs) and its application for cardiovascular disease diagnostics
Eaimkhong S, et al.
Journal of nanomedicine & nanotechnology, 3(144), 2-2 (2012)
Jane A Potter et al.
Journal of virology, 86(23), 12923-12932 (2012-09-21)
The E2 envelope glycoprotein of hepatitis C virus (HCV) binds to the host entry factor CD81 and is the principal target for neutralizing antibodies (NAbs). Most NAbs recognize hypervariable region 1 on E2, which undergoes frequent mutation, thereby allowing the
Wei Wang et al.
Journal of pharmaceutical sciences, 96(1), 1-26 (2006-09-26)
The number of therapeutic monoclonal antibody in development has increased tremendously over the last several years and this trend continues. At present there are more than 23 approved antibodies on the US market and an estimated 200 or more are
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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