I117

R(+)-IAA-94

≥98% (HPLC), solid

• 別名: R(+)-[(6,7-ジクロロ-2-シクロペンチル-2,3-ジヒドロ-2-メチル-1-オキソ-1H-インデン-5-イル)-オキシ]酢酸, R(+)-メチルインダゾン, インダニルオキシ酢酸94
• 実験式（ヒル表記法）: C₁₇H₁₈Cl₂O₄
• CAS番号: 54197-31-8
• 分子量: 357.23
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277844
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: solid
• 光学活性: [α]22/D +36.4°, c = 0.86 in methanol(lit.)
• 色: white
• 溶解性: H₂O: 0.2 mg/mL; 0.1 M NaOH: 2.8 mg/mL; DMSO: >20 mg/mL; ethanol: 20 mg/mL; dilute aqueous acid: insoluble
• 保管温度: 2-8°C
• SMILES記法: C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
• InChI: 1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m1/s1
• InChI Key: RNOJGTHBMJBOSP-QGZVFWFLSA-N

詳細

アプリケーション

R(+)-IAA-94 has been used as a chloride ion channel inhibitor to study its effects on grepafloxacin uptake by human mononuclear (THP-1) cells [1]. It has also been used as a chloride ion channel inhibitor to study its effects on moxifloxacin uptake by human mononuclear (THP-1) cells.[2]

特徴および利点

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)