GEE70092Z

エビ由来アルカリホスファターゼ

Cytiva E70092Z, pack of 1000 U

• UNSPSCコード: 12352204
• NACRES: NA.54

特性

• フォーム: solid
• 包装: pack of 1000 U
• メーカー／製品名: Cytiva E70092Z
• 輸送温度: dry ice
• 保管温度: −20°C

詳細

詳細

Shrimp alkaline phosphatase is a high specific activity, heat-labile alkaline phosphatase. Completely and irreversibly inactivated in Tris buffers at pH 8.0 to 8.5 by heating for 15 min at 65°C. No further treatment is necessary. The ALP (alkaline phosphatase) gene codes for a membrane-bound ectoenzymes that is present in four isoforms and is distributed as tissue nonspecific, intestinal, placenta, and germ cell ALP.[1] The tissue nonspecific enzyme is ubiquitously expressed in a variety of tissues including liver, bone, kidney and is predominant in osteoblasts.[2][1] Alkaline phosphatase is also known as mesenchymal stem cell antigen 1 or tissue nonspecific alkaline phosphatase.[2]

生物化学的／生理学的作用

Alkaline phosphatase hydrolyses pyrophosphate (PPi) to inorganic phosphate and thus maintains a balance between the two forms of phosphate which is highly essential for mineralization.[3][1] Higher levels of serum alkaline phosphatase is found in prostate cancer.[2] Severe TNAP deficiency refers to hypophosphatasia characterized with defective pyridoxal 5′-phosphate metabolism and skeletal hypomineralization.[1]

特徴および利点

• Removing 5′-phosphates from DNA and RNA.
• Easily inactivated by heat.

保管および安定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

アナリシスノート

この製品の分析証明書は、www.cytiva.com.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids