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Merck

G1376

Sigma-Aldrich

L-グルタミン酸 アンモニウム塩

≥99% (TLC)

別名:

(S)-2-アミノペンタン二酸 アンモニウム塩, Glu

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About This Item

化学式:
C5H8NO4 · NH4
CAS番号:
分子量:
164.16
MDL番号:
UNSPSCコード:
12352200
PubChem Substance ID:

アッセイ

≥99% (TLC)

SMILES記法

N.NC(CCC(O)=O)C(O)=O

生物化学的/生理学的作用

L-Glutamic acid is a natural α proteinogenic amino acid use in a wide range of research application including use as a cell culture supplement, enzyme substrate or receptor ligand. L-Glutamine is an agonist at kainate, NMDA, and quisqualate glutamatergic receptors and an excitatory amino acid neurotransmitter.
カイニン酸、NMDA、キスカル酸グルタミン酸作動性受容体のアゴニストであり、興奮性アミノ酸神経伝達物質です。

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M E Flores-Soto et al.
Neurologia (Barcelona, Spain), 27(5), 301-310 (2012-01-06)
To review the physiology of the glutamate receptor subunits such as N-methyl-D-aspartate (NMDA). Glutamic acid (Glu) is the major excitatory neurotransmitter in the central nervous system which interacts with two types classified into two types: metabotropic and ionotropic. Ionotropic receptors
Sandra Stoppelkamp et al.
Journal of neuroscience methods, 194(1), 132-138 (2010-10-19)
The cultivation of pure neuronal cultures is considered advantageous for the investigation of cell-type specific responses (such as transmitter release and also pharmacological agents), however, divergent results are a likely consequence of media modifications and culture composition. Using Fura-2 based
K Sugiyama et al.
Neuroscience, 32(3), 779-791 (1989-01-01)
Several reports have described apparently normal survival and development of hippocampal and spinal cord culture preparations grown in Ham's F-12 medium, which contains 100 microM each of L-glutamate and L-aspartate. As at this concentration these amino acids are neurotoxic, some
Jennifer C M Lau et al.
Molecular vision, 19, 1538-1553 (2013-07-24)
This study investigated changes in the transcript levels of genes related to glutamate neurotransmission and transport as diabetes progresses in the Long-Evans rat retina. Transcript levels of vascular endothelial growth factor (VEGF), erythropoietin, and insulin-like growth factor binding protein 3
V V Kolobov et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (1)(1), 27-32 (2013-06-29)
In experiments on rats showed that intranasal administration of glutamate antibodies in a dose of 300 microg/kg after 1 h after bilateral injection of neurotoxic fragment of beta-amyloid protein (25-35)--Abeta(25-35)--into the Meynert nuclei restores learning ability in the test of

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