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出荷予定日2025年4月15日
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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
IgG fraction of antiserum
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
化学種の反応性
human
テクニック
western blot: 0.5-1 μg/mL using human HeLa cell extract
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CXCR4(7852)
詳細
Chemokine receptor CXCR-4 also refers as fusin or LESTR is a protein that belongs to G-protein coupled receptor 1 family. It is an essential cofactor for T cell-tropic HIV viruses into CD4+ cells. N-Terminal domain and second extracellular loop of the protein act as a HIV binding sites. Anti-CXCR4 (Fusin) (182-196) antibody can be used to block HIV-1 and HIV-2 fusion and infection of human target cells. Rabbit anti-CXCR4 (Fusin) (182-196) antibody reacts specifically with human CXCR4.
免疫原
synthetic peptide corresponding to amino acids 182-196 of the second extracellular loop of human CXCR4.
アプリケーション
Anti-CXCR4 (Fusin) (182-196) antibody may be used in immunoblotting at a working antibody concentration of 0.5 - 1 μg/ml using human HeLa cell extract. It can also be used in immunohistochemistry.
その他情報
The antigen (receptor) is also termed fusin, LESTER and HUMSTR.
物理的形状
Solution in phosphate buffered saline containing 0.02% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
C8352-.1MG:
C8352-BULK:
C8352-VAR:
C8352-.1MG-PW:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
Raji R Nair et al.
NPJ aging and mechanisms of disease, 4, 9-9 (2018-09-06)
One of the major pathological outcomes of DNA damage during aging or anticancer therapy is enhanced inflammation. However, the underlying signaling mechanism that drives this is not well understood. Here, we show that in response to DNA damage, ubiquitously expressed
Karin Jennbacken et al.
The Prostate, 72(8), 913-924 (2012-01-31)
Tasquinimod (ABR-215050) is an orally active quinoline-3-carboxamide analog that has completed phase II clinical trial in patients with castration resistant prostate cancer, showing promising inhibiting effects on the occurrence of metastasis and delayed disease progression. Its mechanism of action is
Verena Schwartz et al.
FEBS letters, 583(17), 2749-2757 (2009-08-12)
MIF is a chemokine-like inflammatory mediator that triggers leukocyte recruitment by binding to CXCR2 and CXCR4. MIF also interacts with CD74/invariant chain, a single-pass membrane-receptor. We identified complexes between CD74 and CXCR2 with a role in leukocyte recruitment. It is
Z Lu et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(12), 6426-6431 (1997-06-10)
The chemokine receptor CXCR4 functions as a fusion coreceptor for T cell tropic and dual-tropic HIV-1 strains. To identify regions of CXCR4 that are important for coreceptor function, CXCR4-CXCR2 receptor chimeras were tested for the ability to support HIV-1 envelope
M Loetscher et al.
The Journal of biological chemistry, 269(1), 232-237 (1994-01-07)
Several chemotactic agonists including interleukin-8 (IL-8) and related cytokines have been shown to activate and attract leukocytes via seven-transmembrane domain, GTP-binding protein-coupled receptors. A cDNA clone, LESTR, encoding a protein of 352 amino acids, corresponding to a novel receptor of
資料
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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