C0605

Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me)フルオロメチルケトン

≥90% (HPLC)

• 別名: Z-DEVD-FMK
• 実験式（ヒル表記法）: C₃₀H₄₁N₄O₁₂F
• CAS番号: 210344-95-9
• 分子量: 668.66
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774802
• MDL number: MFCD23380217
• Assay: ≥90% (HPLC)
• Form: powder

特性

• assay: ≥90% (HPLC)
• form: powder
• color: off-white
• solubility: DMSO: ≥20 mg/mL, clear
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)CC[C@H](NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
• InChI key: GBJVAVGBSGRRKN-JYEBCORGSA-N

詳細

Biochem/physiol Actions

カスパ-ゼ3, 6, 7, 8, 10の細胞透過性インヒビタ-であり、競合的かつ不可逆的に阻害します。

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)