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安全性情報

A2853

Sigma-Aldrich

アゾキシメタン

Practical grade, 13.4 M, ≥90% (GC)

別名:

AOM

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About This Item

化学式:
CH3N=N(→O)CH3
CAS番号:
25843-45-2
分子量:
74.08
MDL番号:
MFCD00126912
UNSPSCコード:
12352200
PubChem Substance ID:
24890698

アッセイ

≥90% (GC)

品質

Practical grade

含みます

≤15% ethanol and acetic acid (Packaged based on azoxymethane.)

組成

methylene chloride, ≤5%

濃度

13.4 M

bp

97-99 °C (lit.)

密度

0.991 g/mL at 25 °C (lit.)

保管温度

−20°C

SMILES記法

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI Key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

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生物化学的／生理学的作用

DNA内でO6-メチルグアニン付加体を誘導し、G→Aの変換を生じさせる発がん物質。実験動物の結腸に腫瘍発生を誘導し、癌の進行と化学予防のメカニズムを研究するのに使用されます。

ピクトグラム

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

シグナルワード

Danger

危険有害性情報

H226,H300,H315,H319,H350,H361d

危険有害性の分類

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2

保管分類コード

3 - Flammable liquids

WGK

WGK 3

引火点(°F)

75.2 °F

引火点(℃)

24 °C

個人用保護具 (PPE)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

PRTR

第一種指定化学物質

消防法

第4類:引火性液体
第二石油類
危険等級III
非水溶性液体

労働安全衛生法名称等を表示すべき危険物及び有害物

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労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

A2853-VAR:
A2853-BULK:
A2853-100MG:
A2853-25MG:

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
089K1157
079K1133
098K1469
098K1488
038K1557

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  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What solvents can be used to dissolve Azoxymethane?

    Azoxymethane is soluble in water, ether, ethanol, and chloroform. The reported solubility in chlorform is 200 mg/mL, and in water is 100 mg/mL.

  7. How should stock solutions of Azoxymethane be stored, and for how long can they be kept?

    No solution stability studies have been performed by Sigma-Aldrich. Because the solution stability is unknown, solutions should be prepared fresh for use.

  8. How does azoxymethane act to cause cancers?

    Azoxymethane is a methylating agent which forms 6-O-methylguanine in DNA.  Unless this methylated base is repaired by cellular enzymes, it results in a base mismatch that subsequently causes tumors in the tissue.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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