A2729

Amisulpride

≥98% (HPLC)

• 別名: 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide, DAN-2163, Deniban
• 実験式（ヒル表記法）: C₁₇H₂₇N₃O₄S
• CAS番号: 71675-85-9
• 分子量: 369.48
• EC Number: 275-831-7
• MDL番号: MFCD00866691
• UNSPSCコード: 12352200
• PubChem Substance ID: 24890689
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated; protect from light
• 色: white
• オーガナイザー: Sanofi Aventis
• 保管温度: 2-8°C
• SMILES記法: O=C(NCC1CCCN1CC)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC
• InChI: 1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
• InChI Key: NTJOBXMMWNYJFB-UHFFFAOYSA-N
• 遺伝子情報: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR6(3362) , HTR7(3363)

詳細

アプリケーション

Amisulpride has been used as a dopamine receptor inhibitor to study its effects on diabetic bone abnormalities in mice.

生物化学的／生理学的作用

Amisulpride is a substituted benzamide derivative. It has a higher affinity towards dopamine receptors in limbic structures than the striatal structures. Amisulpride has a therapeutic effect against schizophrenia.

アミスルプリドはD₂/D₃ドーパミンレセプターに高選択的に作用するアンタゴニストであり、非定型精神病薬です。

特徴および利点

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves