484R-1

PRAME (EP461) Rabbit Monoclonal Primary Antibody

• 別名: Preferentially-expressed Antigen in Melanoma
• UNSPSCコード: 12352203

特性

• 由来生物: rabbit
• 品質水準: 100; 500
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: EP461, monoclonal
• 詳細: For In Vitro Diagnostic Use in Select Regions
• フォーム: buffered aqueous solution
• 交差性: human
• 包装: vial of 0.1 mL concentrate (484R-14); vial of 0.1 mL concentrate Research Use Only (484R-14-RUO); vial of 0.5 mL concentrate (484R-15); vial of 1.0 mL concentrate (484R-16); vial of 1.0 mL concentrate Research Use Only (484R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (484R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (484R-17); vial of 25.0 mL pre-dilute ready-to-use Research Use Only (484R-10-RUO); vial of 25.0 mL pre-dilute ready-to-use (484R-10); vial of 7.0 mL pre-dilute ready-to-use (484R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (484R-18-RUO)
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:50 (concentrated)
• アイソタイプ: IgG
• コントロール: melanoma
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 視覚化: nuclear

詳細

詳細

PRAME (PReferentially-expressed Antigen in MElanoma) is a gene encoded on the 22q11-22 chromosomal sequence and encodes a 509 amino acid residue protein.¹ PRAME is a melanoma antigen that is preferentially expressed in tumors and is recognized by cytotoxic T lymphocytes.^2,3 PRAME can be used to distinguish between malignant melanoma cells and nevus cells,⁴ and therefore may be useful for diagnostic purposes to support a suspected case of melanoma. PRAME is considered a cancer-testis antigen (CTA)⁵ and is not strongly expressed in most other normal tissues. PRAME is positively expressed in about half of uveal melanomas,⁶ and the majority of mucosal melanomas.⁷

品質

• United States - IVD
• Canada - RUO
• European Union - IVD
• Japan - RUO

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and < 0.1% Sodium Azide.

調製ノート

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その他情報

For Technical Service please contact: 800-665-7284 or email: [email protected]

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable