387R-1

Olig2 (EP112) Rabbit Monoclonal Primary Antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100; 500
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: EP112, monoclonal
• 詳細: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• フォーム: buffered aqueous solution
• 交差性: human
• 包装: bottle of 1.0 mL predilute (387R-17); bottle of 7.0 mL predilute (387R-18); vial of 0.1 mL concentrate (387R-14); vial of 0.5 mL concentrate (387R-15); vial of 1.0 mL concentrate (387R-16)
• メーカー／製品名: Cell Marque^®
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• アイソタイプ: IgG
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 遺伝子情報: human ... OLIG2(10215)

詳細

詳細

Olig2, a basic helix–loop–helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas.^1-2 More than half of glioblastomas are weakly positive for Olig2. No Olig2 expression has been found in the non-glial tumors including neuroepithelial tumors, ependymomas, subependymomas, medulloblastomas, and nonneuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and haemangioblastomas.^1-2 In order to characterize cellular subtypes that constitute astrocytomas, oligoastrocytomas and oligodendrogliomas, double labeling of Olig2 and GFAP has been performed which identified two phenotypically distinct tumor populations. The first is Olig2+/GFAP– which has an oligodendroglial morphology, corresponding to pure oligodendrogliomas that contain only oligodendroglial cells; the second is Olig2–/GFAP+ which has an astrocytic phenotype, including not only oligoastrocytomas, but also WHO astrocytomas.^1-2

品質

IVD

IVD

IVD

RUO

関連事項

Olig2 Positive Control Slides, Product No. 387S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: [email protected]

法的情報

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany