676764

テトラヒドロフラン

≥99.0%, ACS reagent, contains 250 ppm BHT as inhibitor, suitable for HPLC

• 別名: オキソラン, テトラメチレンオキシド, ブチレンオキシド
• 実験式（ヒル表記法）: C₄H₈O
• CAS番号: 109-99-9
• 分子量: 72.11
• Beilstein: 102391
• EC Number: 203-726-8
• MDL番号: MFCD00005356
• UNSPSCコード: 12191501
• PubChem Substance ID: 329760651
• NACRES: NA.07

特性

• product name: テトラヒドロフラン, ACS reagent, ≥99.0%, contains 250 ppm BHT as inhibitor
• グレード: ACS reagent
• 蒸気密度: 2.5 (vs air)
• 蒸気圧: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• アッセイ: ≥99.0%
• 形状: liquid
• 自己発火温度: 610 °F
• 含みます: 250 ppm BHT as inhibitor
• expl. lim.: 1.8-11.8 %
• テクニック: HPLC: suitable
• 不純物: ≤0.015% peroxide (as H₂O₂); ≤0.05% water
• 蒸発残留物質: ≤0.03%
• 色: APHA: ≤20
• 屈折率: n20/D 1.407 (lit.)
• pH: ~7
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• 密度: 0.889 g/mL at 25 °C (lit.)
• SMILES記法: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI Key: WYURNTSHIVDZCO-UHFFFAOYSA-N

詳細

詳細

Tetrahydrofuran (THF) is a heterocyclic compound (cyclic ether). It is colorless, has low viscosity, and good solubility in a wide range of solvents. It is widely used as a solvent in organic synthesis, being very popular in reactions with organometallic compounds and Grignard reagents. Due to organic peroxides formation on long term storage, THF is usually stabilized by adding butylated hydroxytoluene (BHT). BHT removes the free radicals required for the peroxide formation.

アプリケーション

Tetrahydrofuran (THF) is used as a solvent in the following processes:

• Organic synthesis

a) Grignard
b) Organometallic compounds
c) Reformatsky
d) Lithiation
e) Hydride reduction
f) Metal-catalyzed coupling (Heck, Stile, Suzuki)
g) Lewis acid mediated reactions

• Crystallization
• Polymerization. Ex. RAFT (Reversible Addition-Fragmentation Chain Transfer) polymerization of p-acetoxystyrene
• Coatings
• As an O-donor ligand to form coordination complexes
• As mobile phase solvent in high-performance liquid chromatography

特徴および利点

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.

その他情報

Go to our Greener Alternative-2-Methyl Tetrahydrofuran - 155810

Go to our Greener Alternative-Cyclopentyl methylether - 675989

安全性情報

• ピクトグラム: GHS02,GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H302,H319,H335,H336,H351
• 注意書き: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 補足的ハザード: EUH019
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): -6.2 °F - closed cup
• 引火点(℃): -21.2 °C - closed cup