PHR1955

メピバカイン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 1-メチル-2′,6′-ピペコロキシリジン 塩酸塩, N-(2,6-ジメチルフェニル)-1-メチル-2-ピペリジンカルボキサミド 塩酸塩
• 実験式（ヒル表記法）: C₁₅H₂₂N₂O · HCl
• CAS番号: 1722-62-9
• 分子量: 282.81
• EC Number: 217-023-9
• MDL番号: MFCD00144738
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 699; traceable to Ph. Eur. M0370000; traceable to USP 1387002
• APIファミリー: mepivacaine
• CofA: current certificate can be downloaded
• 包装: pkg of 500 mg
• アプリケーション: pharmaceutical
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl
• InChI: 1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
• InChI Key: RETIMRUQNCDCQB-UHFFFAOYSA-N
• 遺伝子情報: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.

アプリケーション

Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

局所麻酔薬。一過性のNa⁺内向き電流や定常状態のK⁺外向き電流を可逆的に遮断します。モデル系でタンデムポア型カリウムチャネル(TASK)やKv1.5カリウムチャネルをブロックします。

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAB1955 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301,H336
• 注意書き: P261 - P264 - P270 - P271 - P301 + P310 - P304 + P340 + P312
• 危険有害性の分類: Acute Tox. 3 Oral - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable