PHR1537

オキシテトラサイクリン

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: オキシテトラサイクリン 二水和物
• 実験式（ヒル表記法）: C₂₂H₂₄N₂O₉ · 2H₂O
• CAS番号: 6153-64-6
• 分子量: 496.46
• EC Number: 201-212-8
• MDL番号: MFCD00151234
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823449
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 782; traceable to Ph. Eur. Y0001896; traceable to USP 1491004
• APIファミリー: oxytetracycline
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: -10 to -25°C
• SMILES記法: O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
• InChI: 1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1
• InChI Key: IBZHEBHGZFICKS-IFLJXUKPSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Oxytetracycline is a broad-spectrum antibiotic which finds a wide use in veterinary medicine because of its potential to inhibit the protein synthesis in gram-positive and gram-negative bacteria. It can be used on animal species like cattle, sheep, goats and pigs.

アプリケーション

Oxytetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrofluorimetry techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

Streptomyces rimosusにより産生される抗生物質です。
作用:アミノアシルtRNAが30Sサブユニットに結合するのを妨げることにより、タンパク質合成(伸長)を阻害します。
抗菌スペクトル:グラム陰性菌、グラム陽性菌。
耐性:能動的排出、リボソ-ムの保護、テトラサイクリンの不活性化。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC0364 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS08,GHS09
• シグナルワード: Warning
• 危険有害性情報: H361d,H411
• 注意書き: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危険有害性の分類: Aquatic Chronic 2 - Repr. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable