H7753

ヘキセストロール

analytical standard

• 別名: 4,4′-(1,2-ジエチルエチレン)ジフェノール, meso-3,4-ビス(4-ヒドロキシフェニル)ヘキサン, ジヒドロジエチルスチルベストロール
• 実験式（ヒル表記法）: C₁₈H₂₂O₂
• CAS番号: 84-16-2
• 分子量: 270.37
• Beilstein: 3209460
• EC Number: 201-518-1
• MDL番号: MFCD00068996
• UNSPSCコード: 41116107
• PubChem Substance ID: 329815246
• NACRES: NA.24

特性

• グレード: analytical standard
• 品質水準: 100
• アッセイ: ≥98%
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: forensics and toxicology; pharmaceutical (small molecule); veterinary
• フォーマット: neat
• SMILES記法: CC[C@H]([C@H](CC)c1ccc(O)cc1)c2ccc(O)cc2
• InChI: 1S/C18H22O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,17-20H,3-4H2,1-2H3/t17-,18+
• InChI Key: PBBGSZCBWVPOOL-HDICACEKSA-N
• 遺伝子情報: human ... ESR1(2099) ; rat ... Esr1(24890)

詳細

詳細

Hexestrol is a synthetic nonsteroidal estrogen,[1] which can be used in human medicine as well as a growth promoter in cattle.[2]

アプリケーション

Hexestrol may be used as a reference standard for the determination of the analyte in biological samples using immunoaffinity extraction and gas chromatography-negative-ion chemical ionization mass spectrometry.[2]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生物化学的／生理学的作用

The carcinogen hexestrol is a nonsteroidal synthetic estrogen. Metabolic activation of hexestrol to its quinone, which reacts with DNA to form analogous depurinating adducts, may be a primary critical event leading to oncogenic mutations and cancer initiation.

関連事項

ジエチルスチルベストロールの還元型アナログです。

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H350
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Carc. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 個人用保護具 (PPE): Eyeshields, Gloves, type P3 (EN 143) respirator cartridges