Reacts with HBcAg (epitope recognized - amino acid positions 2-8).
免疫原
Epitope: Core Antigen (ayw)
Recombinant purified HBcAg from E.coli, SDS-denatured
アプリケーション
Research Category 感染症
Research Sub Category 感染症-ウイルス
Anti-Hepatitis B Virus Antibody, core antigen (ayw), clone 10E11, a.a. 2-10 detects level of Hepatitis B Virus & has been published & validated for use in ELISA, IF, IP, WB, IC, IH.
ELISA, immunoblotting, immunofluorescent and immunoperoxidase staining of infected liver tissues and transfected cultured cells. Optimal working dilutions: for immunoblotting - 1:1000; for immunofluorescence - 1:200. Optimal working dilutions must be determined by the end user.
物理的形状
Ascitic fluid. Liquid in DMEM, containing 0.1% sodium azide.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
An E. coli expression system offers a mean for rapid, high yield and economical production of Hepatitis B Virus core (HBc) particles. However, high-level production of HBc particles in bacteria is demanding and optimisation of HBc particle yield from E.
Differentiation of core gene products of the hepatitis B virus in infected liver tissue using monoclonal antibodies
Naoumov, N V, et al
Journal of Medical Virology, 53, 127-138 (1997)
The affinities of monoclonal antibodies against core antigen of hepatitis B virus.
Particulate and denatured core protein as well as e-antigen (HBe) of hepatitis B virus (HBV) differ in part immunologically but this has not been studied in sufficient detail. Therefore, in this study the B-cell immune response to native and denatured
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 69(7), 683-696 (2020-04-30)
Hepatitis B virus X protein (HBx) is a pivotal factor for HBV-induced hepatitis. Herein, we sought to investigate HBx-mediated NLR pyrin domain containing 3 (NLRP3) inflammasome activation and pyroptosis under oxidative stress. The effect of HBx on the NLRP3 inflammasome