ABT142

Anti-PLK-4 Antibody

from rabbit

• 別名: Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase 18, Serine/threonine-protein kinase Sak
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 交差性: mouse, rat, human
• テクニック: immunocytochemistry: suitable; western blot: suitable
• NCBIアクセッション番号: NP_0055079
• UniProtアクセッション番号: O00444
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PLK4(10733)

詳細

詳細

Serine/threonine-protein kinase PLK4 (PLK-4) is a member of the protein kinase superfamily and plays an essential role in centriole duplication. PLK-4 triggers procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins. It may be involved in tumorigenesis since centrosome aberrations are frequently observed in tumors. PLK-4 may also be involved in trophoblast differentiation by phosphorylating HAND1, leading to the disruption between HAND1 and MDFIC and then activating HAND1.

特異性

This antibody recognizes the POLO box domain of PLK-4

免疫原

Epitope: POLO box domain

KLH-conjugated linear peptide corresponding to the POLO box domain of human PLK-4.

アプリケーション

Research Category
細胞骨格

Anti-PLK-4 Antibody detects level of PLK-4 & has been published & validated for use in Western Blotting, ICC.

Research Sub Category
Cytoskeleton

品質

Evaluated by Western Blot in Jurkat cell lysate.

Western Blot Analysis: 0.2 µg/mL of this antibody detected PLK-4 in 10 µg of Jurkat cell lysate.

ターゲットの説明

~95 kDa observed

物理的形状

Protein A purified

Format: Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Jurkat cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable