8.52080

Fmoc-Tyr(2-ClTrt)-OH

Novabiochem^®

• 別名: Fmoc-Tyr(2-ClTrt)-OH, N-α-Fmoc-O-2-chlorotrityl-L-tyrosine
• 実験式（ヒル表記法）: C₄₃H₃₄ClNO₅
• CAS番号: 350241-80-4
• 分子量: 680.19
• MDL番号: MFCD01073759
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥98% (TLC); ≥99.0% (HPLC)
• フォーム: powder
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: hydroxyl
• 保管温度: 2-8°C
• SMILES記法: Clc1c(cccc1)C(Oc4ccc(cc4)C[C@H](NC(=O)OCC5c6c(cccc6)c7c5cccc7)C(=O)O)(c3ccccc3)c2ccccc2
• InChI: 1S/C43H34ClNO5/c44-39-22-12-11-21-38(39)43(30-13-3-1-4-14-30,31-15-5-2-6-16-31)50-32-25-23-29(24-26-32)27-40(41(46)47)45-42(48)49-28-37-35-19-9-7-17-33(35)34-18-8-10-20-36(34)37/h1-26,37,40H,27-28H2,(H,45,48)(H,46,47)/t40-/m0/s1
• InChI Key: XYAWVRLFZHVTNW-FAIXQHPJSA-N

詳細

詳細

The side-chain ClTrt group can be removed with 1% TFA/ 5% TIS in DCM, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support during Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

^[1] K. Barlos, et al. (1998) J. Peptide Res., 51, 194.

関連事項

Replaces: 04-12-1184

アナリシスノート

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Water (K. F.): ≤ 4.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable