8.51014

Fmoc-OSu

≥99.0% (HPLC), for peptide synthesis, Novabiochem^®

• 別名: Fmoc-OSu, FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
• 実験式（ヒル表記法）: C₁₉H₁₅NO₅
• CAS番号: 82911-69-1
• 分子量: 337.33
• MDL番号: MFCD00010733
• UNSPSCコード: 12352108
• EC Index Number: 433-520-5
• NACRES: NA.22

特性

• product name: Fmoc-OSu, Novabiochem^®
• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥99.0% (HPLC)
• 形状: powder
• メーカー／製品名: Novabiochem^®
• mp: 145-148 °C
• アプリケーション: peptide synthesis
• 官能基: Fmoc
• 保管温度: 2-8°C
• InChI: 1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2
• InChI Key: WMSUFWLPZLCIHP-UHFFFAOYSA-N

詳細

詳細

Reagent for the preparation of pure Fmoc-amino acids that are free from contamination by Fmoc-dipeptides ^[1,2,3].

Literature references

^[1] A. Paquet (1982) Can. J. Chem., 60, 976.
^[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
^[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.

アプリケーション

• Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion: This study uses Fmoc-OSu for selective functionalization of amines, demonstrating its role in synthesizing complex molecules with specific adhesive properties (Fischer et al., 2020).
• Fmoc-OASUD: A new reagent for the preparation of Fmoc-amino acids free from impurities resulting from Lossen rearrangement: Discusses the development of Fmoc-OASUD as a superior alternative to Fmoc-OSu, reducing impurities in peptide synthesis processes (Rao et al., 2016).

関連事項

Replaces: 01-63-0001

アナリシスノート

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302 - H317 - H411
• 注意書き: P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable