850346C

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

• 別名: 1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))
• 実験式（ヒル表記法）: C₃₆H₆₈NO₈P
• CAS番号: 56750-90-4
• 分子量: 673.90
• MDL番号: MFCD07784458
• UNSPSCコード: 51191904
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: liquid
• 包装: pkg of 1 × 2.5 mL (850346C-25mg); pkg of 2 × 4 mL (850346C-200mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 850346C
• 濃度: 10 mg/mL (850346C-25mg); 25 mg/mL (850346C-200mg)
• 脂質タイプ: cardiolipins; phospholipids
• 輸送温度: dry ice
• 保管温度: −20°C

詳細

詳細

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.[1]

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[2] It is also an important component of the mucosal layer of the colon.[3]

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

アプリケーション

14:1 (Δ9-Cis) PC has been used in the liposome preparation.[4] It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.[5]

生物化学的／生理学的作用

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells.[1] PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia.[6] Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.[7]

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[3] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[6]

包装

5 mL Clear Glass Sealed Ampule (850346C-200mg)

5 mL Clear Glass Sealed Ampule (850346C-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H331,H336,H351,H361d,H372
• 注意書き: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• ターゲットの組織: Liver,Kidney, Respiratory system
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 引火点(°F): does not flash
• 引火点(℃): does not flash