479179

(S)-(−)-4-ヒドロキシ-2-ピロリジノン

97%

• 別名: (S)-β-ヒドロキシ-γ-ブチロラクタム
• 実験式（ヒル表記法）: C₄H₇NO₂
• CAS番号: 68108-18-9
• 分子量: 101.10
• Beilstein: 1524192
• MDL番号: MFCD00273370
• UNSPSCコード: 12352005
• PubChem Substance ID: 24871604
• NACRES: NA.22

特性

• アッセイ: 97%
• 光学活性: [α]23/D −43°, c = 1 in ethanol
• mp: 156-159 °C (lit.)
• 官能基: hydroxyl
• SMILES記法: O[C@@H]1CNC(=O)C1
• InChI: 1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m0/s1
• InChI Key: IOGISYQVOGVIEU-VKHMYHEASA-N

詳細

詳細

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.[1]

アプリケーション

(S)-(−)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:

• Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.[2]
• Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.[3]

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H318
• 注意書き: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)