460923

Propargyl chloroformate

96%

• 別名: (Prop-2-ynyloxy)carbonyl chloride, 2-Propyn-1-yl carbonochloridate, 2-Propynyl chloroformate, Prop-2-yn-1-yl carbonochloridate, Propargyloxycarbonyl chloride
• 化学式: HC≡CCH₂OCOCl
• CAS番号: 35718-08-2
• 分子量: 118.52
• Beilstein: 1745399
• MDL番号: MFCD00270127
• UNSPSCコード: 12352100
• PubChem Substance ID: 24869771
• NACRES: NA.22

特性

• 蒸気圧: 0.65 psi ( 20 °C)
• アッセイ: 96%
• 反応適合性: reaction type: click chemistry
• 屈折率: n20/D 1.435 (lit.)
• bp: 118-122 °C (lit.)
• 密度: 1.215 g/mL at 25 °C (lit.)
• 保管温度: 2-8°C
• SMILES記法: ClC(=O)OCC#C
• InChI: 1S/C4H3ClO2/c1-2-3-7-4(5)6/h1H,3H2
• InChI Key: RAMTXCRMKBFPRG-UHFFFAOYSA-N

詳細

詳細

Propargyl chloroformate is a propargyl ester. It serves as a protecting group for the hydroxy and amino functional group. Rates of solvolysis of propargyl chloroformate has been analyzed in various solvents of widely varying nucleophilicity and ionizing power values using the extended Grunwald-Winstein equation.

アプリケーション

Propargyl chloroformate may be used for the preparation of the following:

• binaphthol-diacetylene derivatives
• propargyl pentafluorophenyl carbonate
• N-Poc protected amino acids (Poc = propargyloxycarbonyl)

安全性情報

• ピクトグラム: GHS02,GHS06,GHS05
• シグナルワード: Danger
• 危険有害性情報: H226,H302,H311 + H331,H314
• 注意書き: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 86.0 °F - closed cup
• 引火点(℃): 30 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter