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Merck

TP53

tumor protein p53

別名:
BCC7, LFS1, P53, TRP53
Species:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...詳細
UniProtKB ID:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
遺伝子ID:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • sheep(443421) tumor protein p53
  • cow(281542) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53

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ELISA

製品番号
詳細
Species
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
RAB0910
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
MABE339
抗p53（野生型）抗体、クローンPAb1620, clone Pab1620, from mouse,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot
OP43
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
交差性
feline, human
アプリケーション
OP29
Anti-p53 (Ab-3) (Mutant) Mouse mAb (PAb240), liquid, clone PAb240, Calbiochem®,
交差性
bovine, chicken, hamster, human, mouse, rat
アプリケーション
OP33
Anti-p53 (Ab-5) (Wild type) Mouse mAb (PAb1620), liquid, clone PAb1620, Calbiochem®,
交差性
bovine, human, mouse, primate, rat
アプリケーション
P6874
Anti-p53 antibody, Mouse monoclonal, clone DO-1, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot

Cell Lines

製品番号
詳細
Species
CLLS1049
MCF10A 細胞 TP53 (-/-), ,
Species
human
CLLS1007
SW48細胞TP53 -/-, ,
Species
human
CLLS1127
DLD1細胞 TP53 -/-, ,
Species
human

Proteins

製品番号
詳細
Species
23-034-M
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Species
14-865
p53-GST (recombinant protein), ,
Species
P6249
p53 ヒト, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Species
human
P6374
p53 ヒト, recombinant, expressed in baculovirus infected Sf21 cells,
Species
human
SRP2108
p53 (1-81)、変異株、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
EHU123221
MISSION® esiRNA, targeting human TP53,
Species
human