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Merck

SCN11A

sodium channel, voltage-gated, type XI, alpha subunit

別名:
NAV1.9, NaN, SCN12A, SNS-2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(11280) Summary: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004]
  • Mouse(24046) sodium channel, voltage-gated, type XI, alpha
  • Rat(29701) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic guinea pig(100734219) sodium channel, voltage-gated, type XI, alpha subunit
  • Domestic Rabbit(100349709) sodium channel, voltage-gated, type XI, alpha subunit
  • sheep(101117022) sodium channel, voltage-gated, type XI, alpha subunit
  • cow(535956) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic cat(101085312) sodium channel, voltage-gated, type XI, alpha subunit
  • dog(485593) sodium channel, voltage-gated, type XI, alpha subunit
  • naked mole-rat(101723747) sodium channel, voltage-gated, type XI, alpha subunit

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-Sodium Channel NaV1.9 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
交差性
rat
アプリケーション
western blot
モノクロナール抗ナトリウムチャネル, Pan マウス宿主抗体, ~1 mg/mL, clone K58/35, purified immunoglobulin,
交差性
mammals
アプリケーション
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

製品番号
詳細
Species
リドカイン 塩酸塩 一水和物, solid,
Species
human
リドカイン 塩酸塩 一水和物, United States Pharmacopeia (USP) Reference Standard,
Species
human
リドカイン, United States Pharmacopeia (USP) Reference Standard,
Species
human
プロカイン 塩酸塩, ≥97%,
Species
human
プロカインアミド 塩酸塩, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
ラモトリジン, ≥98%, powder,
Species
rat, human
カルバマゼピン, powder,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SCN11A,
Species
human