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MBP

myelin basic protein

別名:
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
  • Mouse(17196) myelin basic protein
  • Rat(24547) myelin basic protein
  • chicken(396217) myelin basic protein
  • domestic cat(101096421) myelin basic protein
  • dog(476160) myelin basic protein
  • sheep(101109407) myelin basic protein
  • cow(618684) myelin basic protein
  • naked mole-rat(101702488) myelin basic protein
  • domestic guinea pig(100731253) myelin basic protein

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Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2829, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Myelin Basic Protein Mouse mAb (SMI-99), liquid, clone SMI-99, Calbiochem®,
交差性
guinea pig, mammals
アプリケーション
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2827, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗MBP抗体, affinity isolated antibody,
交差性
dog, guinea pig, horse, human, rabbit, rat
アプリケーション
western blot
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant,
交差性
chicken, horse, human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

Proteins

製品番号
詳細
Species
ミエリン塩基性タンパク質 ウシ, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
Species
cow
ミエリン塩基性タンパク抗原 ヒト脳由来, ≥95% (SDS-PAGE),
Species
human
MBP, Dephosphorylated, ,
Species
cow
MBP(ミエリン塩基性タンパク質)、ウシ、精製済み, ,
Species
cow
ミエリン塩基性タンパク質 from guinea pig brain, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
Species
domestic guinea pig

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MBP,
Species
human