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Merck

KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1

別名:
KIR1.1, ROMK, ROMK1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
  • Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
  • chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
  • Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
  • cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
  • dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
  • naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1

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Small Molecule - Activator

製品番号
詳細
Species
ジアゾキシド, ,
Species
rat, mouse, human

Small Molecule - Antagonist

製品番号
詳細
Species
クロマカリム, ,
Species
rat
Glyburide, meets USP testing specifications,
Species
rat, human
グリベンクラミド, ≥99% (HPLC),
Species
rat, human
クロルプロパミド, analytical standard, ≥97%,
Species
human, mouse
トルブタミド, analytical standard,
Species
human, mouse

Antibodies

製品番号
詳細
交差性
アプリケーション
抗KCNJ1 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗KCNJ1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
dog, guinea pig, horse, human, rabbit, rat
アプリケーション
western blot
Anti-ROMK antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
抗KCNJ1抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Blocker

製品番号
詳細
Species
グリクラジド, powder, ≥98%,
Species
human
グリメピリド, ≥98% (HPLC), solid,
Species
human
レパグリニド, ≥98% (HPLC), solid,
Species
human
グリピジド, solid,
Species
human
Glyburide, meets USP testing specifications,
Species
rat, human

Small Molecule - Inhibitor

製品番号
詳細
Species
Linopirdine, ≥98% (HPLC),
Species
rat
VU591, ≥98% (HPLC),
Species
human
テルティアピン-Q トリフルオロアセタート塩, ≥97% (HPLC),
Species
rat, human, mouse
クロルプロパミド, analytical standard, ≥97%,
Species
human, mouse
トルブタミド, analytical standard,
Species
human, mouse

Small Molecule - Ligand

製品番号
詳細
Species
グリメピリド, ≥98% (HPLC), solid,
Species
human
グリピジド, solid,
Species
human
グリベンクラミド, ≥99% (HPLC),
Species
rat, human
クロルプロパミド, analytical standard, ≥97%,
Species
human, mouse

Small Molecule - Opener

製品番号
詳細
Species
ミノキシジル, ≥99% (TLC),
Species
human
ジアゾキシド, ,
Species
rat, mouse, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human KCNJ1,
Species
human