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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

別名:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Species:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...詳細
UniProtKB ID:
P28222, Q4VAY7
遺伝子ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

製品番号
詳細
Species
S1198
コハク酸スマトリプタン, ≥98% (HPLC), solid,
Species
human
SML0248
Zolmitriptan, ≥98% (HPLC),
Species
human
1457469
ナラトリプタン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
1286413
Frovatriptan succinate, United States Pharmacopeia (USP) Reference Standard,
Species
human
1642201
コハク酸スマトリプタン, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
G5793
GR 127935 塩酸塩 水和物, >98% (HPLC), powder,
Species
human
M149
メチオテピン メシル酸塩, ≥98% (HPLC), solid,
Species
human
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
P8688
(S)-(−)-プロプラノロール 塩酸塩, ≥98% (TLC), powder,
Species
human
M137
メチセルジド マレイン酸塩, solid,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
MABN1539
抗セロトニン受容体1B抗体、クローン1C2.1, clone 1C2.1, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
western blot
SAB2500924
抗セロトニンレセプター 1B/HTR1B ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Blocker

製品番号
詳細
Species
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
P8688
(S)-(−)-プロプラノロール 塩酸塩, ≥98% (TLC), powder,
Species
human
T3146
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
Z101
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
F1553
S-(+)-フルオキセチン 塩酸塩, ≥98% (HPLC), solid,
Species
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F132
フルオキセチン 塩酸塩, solid,
Species
human
R0875
レセルピン, ,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
H8876
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

製品番号
詳細
Species
H9772
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

esiRNA

製品番号
詳細
Species
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
Species
mouse