DNASE1
deoxyribonuclease I
別名:
DNL1, DRNI
Species:
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), naked mole-rat Dnase1 (101713435), domestic guinea pig Dnase1 (100718441), sheep DNASE1 (101122154), Horse DNASE1 (100034219), cow DNASE1 (282217), Domestic Rabbit DNASE1 (100009513), dog DNASE1 (403413) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, human, rat
アプリケーション
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
交差性
bovine, human, rat
アプリケーション
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
交差性
bovine, human, rat
アプリケーション
Proteins
製品番号
詳細
Species
デオキシリボヌクレアーゼ I ウシ膵臓由来, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Species
デオキシリボヌクレアーゼ I ウシ膵臓由来, Type II, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Species
組み換え型デオキシリボヌクレアーゼI, grade I, from bovine pancreas, expressed in Pichia pastoris,
Species
cow